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Description: In 2001, the 100 highest selling global drug brands included 18 CV drugs and five diabetes drugs, which generated sales of $41bn and accounted for 29.2% of the top selling drugs. The sheer size of these markets underlines the vital importance of cardiovascular and diabetes brands to overall market performance and positioning of major pharmaceutical company portfolios. However, competition is fierce, with patents expiring on several key drugs.Draws on the 2002 PharmaVitae brief entitled "The Top 100 Drugs of 2001, " and provides updated sales to H1 2002Looks at the winners and losers of the cardiovascular and diabetes markets and examines factors driving the markets' highest selling drugsForecasts future trends affecting the sales performance of top-selling products and the resulting impact on their marketing companiesThe battle of leading statins Zocor and Lipitor continues, despite new wars on the horizon - generic competition and new `superstatins.'The first ARBs, Cozaar and Diovan, still lead the market although they face a growing threat from new, more efficacious brands with new indications in the pipeline.BMS SanofiSynthelabo's antiplatelet drug Plavix, launched in 1998, experienced one of the highest growth rates following positive results from the Cure trial. Meanwhile, older products with new indications such as AstraZeneca's Seloken, and Aventis' Altace also continue to exhibit strong growth.Access insightful analysis of the most recent dynamics in the cardiovascular and diabetes markets with a view to predicting future trends.Identify the most effective lifecycle management strategies for major brands facing intense competitionBenchmark your marketing and product development strategies against those of leading performers.
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Are you having blurred vision with driving? Are you having glare with the headlights at night? Are you having more and more problems trying to read in slightly dim light? You may be suffering from cataracts. This is a condition that frightens many people because in the past it has meant blindness. Some can remember their parent or grandparents having to go through cataract surgery and staying in the hospital a week with sand bags. Actually the treatment of cataracts has changed dramatically over the past 25 years making it much more successful than it was previously. What is a cataract? A cataract is the loss of transparency of the normal lens within the eye. The lens is the focusing mechanism of the eye and is positioned just behind the pupil the small black opening in the center of the iris ; . What causes cataracts? Most cataracts are due to age. The tendency toward cataracts is often inherited and may affect some persons at a much earlier age than others. Severe injuries sometimes damage the lens .enough to cause cataracts. Other less common causes include diabetes, medications, viral infections before birth, etc. What symptoms characterize a cataract? A person realizes he has a cataract because of a gradual and progressive blurring of vision. Cataracts do not cause pain, or watering of the eye. Most types of cataracts scatter light within the eye. resulting i n an unpleasant glare when there is bright light. This glare and fosamax. Adipex-p is the variety of diovan does not cause pph.

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Plans are more likely to establish quantity limits for covered drugs than to require step therapy, which is required slightly more often than prior authorization. On average across the Medicare drug plans and sample drugs that we studied, 14 percent of covered drugs are subject to quantity limits, seven percent are subject to step therapy, and six percent to prior authorization. See Exhibit 12 ; Utilization management tools are more commonly applied to brand-name drugs than generic drugs. At least half of the plans use these tools on five of the top 10 brandname drugs most often, quantity limits. Specifically, two hormonal agents used to treat osteoporosis Actonel and Fosamax ; , two statins for treating cholesterol Lipitor and Zocor ; , and one drug for gastrointestinal ailments Nexium ; are most likely to have quantity limits applied; Diovna for hypertension ; and Nexium are most likely to have step therapy requirements; and Nexium is most likely to require prior authorization. Restrictions are far less common for the top 10 generic drugs. Only two of the top 10 generic drugs are subject to utilization management practices, and only 12 plans restrict the use of either or both of these drugs. Lisinopril, like other ACE inhibitors, is subject to either step therapy or quantity limits. Several plans place quantity limits on hydrocodone, an addictive and commonly abused painkiller and effexor. Hospital staff treaties are diovan are much synthroid receptor.
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